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ThalassaemiaFACT:The World Health Organisation (WHO) estimates that globally at least 5% of adults are genetic carriers for a haemoglobin condition.THALASSAEMIA AND GENETIC BLOOD DISORDERSThalassaemia is the name given to a group of genetically inherited blood disorders. These disorders affect haemoglobin production in the red blood cells. Haemoglobin is a protein in the blood cells that carries oxygen around our bodies and is made up of two very important protein chains Alpha (a) and Beta (b) globin. Thalassaemia is passed on from parent and child through the genes. Genes carry information about human characteristics such as eye colour, hair colour and haemo(globin). Some changes occur to genes, resulting in medical conditions. The globin genes carry information for individuals to make haemoglobin, however changes in the globin genes can result in the following: Beta Thalassaemia Majora severe anaemia requiring life long treatment, including monthly blood transfusions. Alpha thalassaemiaone type can be fatal for baby and dangerous for mother during pregnancy. Sickle cell anaemiaa condition which may require regular blood transfusions. Extremely painful blockages of blood vessels occur throughout life due to changes in shape of the red blood cells. Haemoglobin Eusually a benign condition, but if inherited with beta thalassaemia or sickle cell, can result in severe condition requiring life long treatment.
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